Tax Questions: Must I Claim Plasma Donation Income & IRA Withdrawal Tax Withholding?
I've got a couple tax questions that have been bothering me lately and would appreciate some advice. First, I've been supplementing my income by selling plasma at local donation centers. Is there some minimum amount I can earn from plasma donations before I have to report it on my taxes? And if I donate at multiple centers in my area, is the threshold based on what I make at each individual place, or do I need to add up everything I make from all centers combined? Second, I have an old IRA that I haven't contributed to in probably 5-6 years, and I'm thinking about taking some money out since I could really use the cash right now. When I called my financial institution, they wouldn't tell me what tax bracket I'm in so I could figure out how much to withhold for taxes. I've done some research online and have a rough idea of my bracket, but I'm not sure if I should just withhold that percentage or maybe take out a bit more to be safe and possibly get a refund next tax season. Any guidance would be greatly appreciated!
21 comments


Sofia Torres
Both great questions that many people wonder about! For plasma donations, the IRS considers this "other income" and technically all income is taxable regardless of amount. Unlike independent contractor work, there's no $600 threshold before they're required to send you a 1099. However, in practice, if you're making less than $600 total from all plasma centers combined, you may not receive any tax forms, but you're still supposed to report it. The total is cumulative across all centers - the IRS looks at your total income, not per company. Regarding your IRA withdrawal, your financial institution can't technically tell you what tax bracket you're in because they don't have your complete financial picture. IRA withdrawals are generally subject to a 10% early withdrawal penalty if you're under 59½ (with some exceptions) plus your regular income tax rate. Rather than guessing, I'd recommend withholding at least 20-25% for federal taxes to be safe. You can always get a refund if it's too much, but coming up short could mean penalties. Also, don't forget about state taxes if applicable in your area.
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Dmitry Sokolov
•Thanks for the info! Quick question on the plasma thing - if the donation center doesn't send me any tax forms, how would the IRS even know I'm making that money? Do they somehow track this?
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Sofia Torres
•Great question. The IRS may not immediately know about unreported plasma donation income since there might not be tax forms issued for smaller amounts. However, this doesn't mean you're exempt from reporting it. The IRS can discover unreported income through various methods including bank deposits, lifestyle audits, or if you're selected for a random audit. Additionally, if you receive payment by check or electronic transfer, there's a paper trail. Remember that deliberately failing to report income is technically tax evasion. The risk may seem small for smaller amounts, but it's still a legal obligation to report all income regardless of whether you receive a 1099 or other tax form. Better to report everything properly than risk penalties and interest if discovered later.
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Ava Martinez
I worked at a tax prep office for a few years and wanted to share my experience with Taxr.ai (https://taxr.ai) which really helped me understand situations like yours. After dealing with dozens of clients with "other income" questions similar to yours, I found this tool super helpful. For your plasma situation, they can actually analyze documentation from donation centers and tell you exactly how to report it. What's cool is they'll look at your specific situation and tell you if you need to file a Schedule C or just report it as other income on Schedule 1. For your IRA question, they have a withholding calculator that's way more accurate than guessing. I was in a similar situation last year with an old 401k, and their system calculated the exact amount I should withhold based on my full financial picture.
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Miguel Ramos
•How does this work exactly? Do I need to upload all my financial documents? Seems like a privacy concern letting some random website see all my tax info...
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QuantumQuasar
•Can it actually tell me what tax bracket I'm in? My financial institution was completely useless when I asked them this question. Also, does it cost money?
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Ava Martinez
•You only need to upload the specific documents related to the question you're asking - so for plasma donations, just those receipts or statements. They use bank-level encryption and don't store your docs after analysis, so your privacy is protected. I was concerned about that too, but their security measures are solid. The tool absolutely can tell you what tax bracket you're in based on your complete financial picture. Unlike your financial institution (which only sees part of your finances), taxr.ai looks at all income sources to determine your actual tax bracket. They also show you marginal vs. effective tax rates which was eye-opening for me. As for cost, I'd rather not discuss pricing here, but I found the value well worth it compared to the mistakes it helped me avoid.
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Miguel Ramos
Just wanted to follow up about my experience with taxr.ai. I was skeptical at first (as you could probably tell from my comment), but I decided to give it a try since I had a similar situation with income from medical studies and plasma donation. I uploaded my donation receipts and last year's tax return, and the system immediately showed me how to properly report everything. Turns out I was doing it wrong for years! It showed me that since I was donating regularly, I should have been tracking mileage to the donation centers as well, which is deductible if you itemize. Also gave me a clear breakdown of my actual tax bracket so I could make better decisions. Their withholding calculator for my upcoming 401k rollover was super helpful too. Definitely less stressful than guessing and potentially getting hit with penalties.
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Zainab Omar
Been through both these situations before. For the IRA withdrawal, I spent HOURS trying to get through to the IRS to confirm the right withholding amount and kept getting disconnected or stuck on hold. Super frustrating waste of time. Then I found out about this service called Claimyr (https://claimyr.com) - they have this system that gets you connected to an actual IRS agent without the wait. You can see how it works here: https://youtu.be/_kiP6q8DX5c. I was skeptical but desperate after wasting an entire afternoon on hold. Anyway, they got me through to an IRS agent in about 20 minutes who confirmed exactly what my withholding should be based on my tax situation. The agent even explained some exceptions to the early withdrawal penalty that might apply to my situation that I had no idea about.
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Connor Gallagher
•How does this even work? I've literally spent DAYS trying to reach the IRS over the years and never get through. What's the catch?
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Yara Sayegh
•Yeah right... nobody gets through to the IRS these days. Last time I tried I was on hold for 2+ hours before getting disconnected. I'll believe it when I see it.
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Zainab Omar
•There's no special magic to it - they use technology that monitors the IRS phone queues and algorithms to predict wait times. When a spot opens up, their system secures your place in line and calls you when an agent is about to be available. It's basically like having someone wait on hold for you, but using tech to do it efficiently. The biggest advantage is that they can call multiple IRS numbers simultaneously to find the shortest queue, something we can't do as individuals. It's just a more efficient approach to the existing system. The IRS even acknowledges these types of services exist because they help distribute call volume more efficiently. I was definitely skeptical too until I actually got through to a human at the IRS who answered all my questions about IRA withholding.
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Yara Sayegh
Well, I have to eat my words about Claimyr. After posting my skeptical comment, I figured I'd try it since I needed to ask about some back taxes anyway. I've been trying for THREE WEEKS to get through to the IRS about a payment plan question. Used Claimyr yesterday and got connected to an agent in about 35 minutes. The agent actually helped me set up an installment agreement and explained exactly how my withholding should work for my upcoming IRA withdrawal. For the OP's question - the agent told me that withholding should generally be at least your marginal tax rate plus 10% for the early withdrawal penalty if applicable. For me that worked out to 32% total. Better to overwithhold than underwithhold and face penalties.
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Keisha Johnson
Just a heads up on the plasma donation income - I used to work at a plasma collection center. Most places report income to the IRS once it exceeds $600 in a calendar year, but some smaller places don't. Either way, you're legally required to report ALL income regardless of whether you get a tax form. Also, be aware that the IRS considers plasma donation as "income" not a "donation" because you're being compensated. This is different from blood donation which is usually unpaid and not taxable.
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Paolo Longo
•So what form do you use to report plasma money if you don't get a 1099? I made like $400 last year and didn't report it...did I mess up?
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Keisha Johnson
•You would report it on Schedule 1 as "Other Income" - there's a specific line for this. Just write "Plasma Donation" as the description and include the total amount you received. Even without a 1099, you're still required to report it. For just $400, it's not likely to trigger any issues, but technically you should have reported it. The impact on your taxes would have been relatively small - basically just your tax rate times that $400. Going forward, I'd recommend keeping records of all your plasma donations and reporting the income properly. If you're doing it regularly, you might even consider keeping track of mileage to and from donation centers as that could potentially be deductible if you itemize deductions.
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CosmicCowboy
For your IRA question - I work in retirement planning. The withholding decision depends on a few things: 1. Is this a traditional IRA or Roth IRA? Traditional will be taxed as regular income, Roth withdrawals are generally tax-free if you meet certain requirements. 2. How old are you? If under 59½, you'll typically face a 10% early withdrawal penalty unless you qualify for an exception (like first-time home purchase, certain medical expenses, etc). 3. How much are you withdrawing? Large withdrawals could push you into a higher tax bracket. Safe bet is to withhold at least 20% federal plus state tax if applicable, maybe more if it's a large amount. Better to get a refund than owe penalties.
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Dylan Campbell
•Thanks for this breakdown! It's a traditional IRA and I'm 43, so I know I'll get hit with that early withdrawal penalty. I'm planning to take out about $8,000 - not my whole balance but enough to help with some unexpected expenses that came up. Based on what everyone's saying, sounds like I should withhold at least 25% to be safe?
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CosmicCowboy
•Yes, withholding 25% would be a smart move in your situation. With a traditional IRA withdrawal at age 43, you'll definitely face the 10% early withdrawal penalty unless you qualify for one of the exceptions (like using it for qualified higher education expenses, certain medical expenses exceeding 7.5% of your AGI, first-time home purchase up to $10,000, etc.). For an $8,000 withdrawal, if your current tax bracket is around 15% federal, adding the 10% penalty means you should withhold at least 25%. Don't forget to account for state taxes too if your state taxes retirement distributions. Some people even withhold 30% to be extra safe. While it might feel like you're getting less money now, it's better than facing an unexpected tax bill plus potential underpayment penalties when you file your return next year.
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Lucas Parker
@Dylan Campbell - I'd also suggest checking if any of the early withdrawal penalty exceptions apply to your situation before you pull the trigger on that $8,000 withdrawal. The IRS allows penalty-free withdrawals for things like unreimbursed medical expenses that exceed 7.5% of your adjusted gross income, qualified higher education expenses, or if you're unemployed and using it for health insurance premiums. Also, another option to consider - instead of a lump sum withdrawal, you might want to look into substantially equal periodic payments (SEPP) under IRS Rule 72(t). This lets you take regular distributions from your IRA before age 59½ without the 10% penalty, though you have to commit to taking payments for at least 5 years or until you reach 59½, whichever is longer. Given that this is for unexpected expenses, a one-time withdrawal probably makes more sense, but it's worth knowing all your options. The 25-30% withholding recommendation from others here is solid advice - better to overwithhold and get money back than face penalties next April.
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CosmicCaptain
•This is really helpful information about the penalty exceptions! I hadn't heard of the SEPP option before. My situation is mainly due to some unexpected car repairs and medical bills, so I'm not sure if I'd qualify for the medical expense exception since I'd have to calculate if it exceeds 7.5% of my AGI. The periodic payment option sounds interesting but probably too restrictive for my current needs - I really just need this one-time amount to get back on my feet. I think I'll stick with the lump sum withdrawal and go with the 25-30% withholding as everyone's suggesting. Thanks for laying out all these options though - it's good to know there are alternatives for future reference!
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